Antibodies are critical for adaptive immunity and represent the primary correlate of protection for most vaccines. They are also an important type of therapeutic with rapidly growing demand.
The antibody biology lab, headed by Patrick Wilson, studies various aspects of antibody-mediated immunity. These topics include antibody-mediated immunity to infectious diseases such as influenza, anthrax, pneumococcal and staphylococcal bacteria. We also study the function of B cells, the development of B cell immune responses, antibody gene usage and diversification, and B cell tolerance.