Publications

110. Bernstein DI, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, Wilson PC, Solórzano A, Van der Wielen M, Walter EB, Albrecht RA, Buschle KN, Chen YQ, Claeys C, Dickey M, Dugan HL, Ermler ME, Freeman D, Gao M, Gast C, Guthmiller JJ, Hai R, Henry C, Lan LYL, McNeal M, Palm AKE, Shaw DG, Stamper CT, Sun W, Sutton V, Tepora ME, Wahid R, Wenzel H, Wohlbold TJ, Innis BL, García-Sastre A, Palese P, Krammer F. Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial. The Lancet infectious diseases. 2019. [Epub ahead of print.]

109. Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, Johnson SJ, Gill K, Cervasi B, Zou J, Bretin A, Hahn M, Gewirtz AT, Bosinger SE, Wilson PC, Li S, Alter G, Khurana S, Golding H, Pulendran B. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 2019; 178(6):1313-1328.e13.

108. Lee JM, Eguia R, Zost SJ, Choudhary S, Wilson PC, Bedford T, Stevens-Ayers T, Boeckh M, Hurt AC, Lakdawala SS, Hensley SE, Bloom JD. Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin. eLife. 2019; 8:e49324.

107. Henry C, Palm AE, Utset HA, Huang M, Ho IY, Zheng NY, Fitzgerald T, Neu KE, Chen YQ, Krammer F, Treanor JJ, Sant AJ, Topham DJ, Wilson PC. Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study. Journal of virology. 2019; 93(21):e01150-19.

106. Wan H, Gao J, Yang H, Yang S, Harvey R, Chen YQ, Zheng NY, Chang J, Carney PJ, Li X, Plant E, Jiang L, Couzens L, Wang C, Strohmeier S, Wu WW, Shen RF, Krammer F, Cipollo JF, Wilson PC, Stevens J, Wan XF, Eichelberger MC, Ye Z. The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. Nature microbiology. 2019. [Epub ahead of print.]

105. Tan C, Mueller JL, Noviski M, Huizar J, Lau D, Dubinin A, Molofsky A, Wilson PC, Zikherman J. Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery. Journal of immunology. 2019; 202(10):2907-2923.

104. Henry C, Zheng NY, Huang M, Cabanov A, Rojas KT, Kaur K, Andrews SF, Palm AE, Chen YQ, Li Y, Hoskova K, Utset HA, Vieira MC, Wrammert J, Ahmed R, Holden-Wiltse J, Topham DJ, Treanor JJ, Ertl HC, Schmader KE, Cobey S, Krammer F, Hensley SE, Greenberg H, He XS, Wilson PC. Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals. Cell host & microbe. 2019; 25(3):357-366.e6.

103. Guthmiller JJ, Dugan HL, Neu KE, Lan LY, Wilson PC. An Efficient Method to Generate Monoclonal Antibodies from Human B Cells. Methods in molecular biology. 2019; 1904:109-145.

102. McGargill MA, Pillai MR, Chang TC, Crawford J, Keating R, Labombarde J, Lewis C, Guthmiller J, Li QZ, Wilson PC, Thomas P. Autoreactive potential of universal influenza vaccines. Journal of immunology. 2019; 202 (1 Supplement) 74.6.

101. Chen YQ, Lan LY, Huang M, Henry C, Wilson PC. Hemagglutinin Stalk-Reactive Antibodies Interfere with Influenza Virus Neuraminidase Activity by Steric Hindrance. Journal of virology. 2019; 93(4):e01526-18.

100. Neu KE, Guthmiller JJ, Huang M, La J, Vieira MC, Kim K, Zheng NY, Cortese M, Tepora ME, Hamel NJ, Rojas KT, Henry C, Shaw D, Dulberger CL, Pulendran B, Cobey S, Khan AA, Wilson PC. Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination. The journal of clinical investigation. 2019; 129(1):93-105.

99. Krammer F, Wilson PC. Editorial overview: Tough targets. Current opinion in immunology. 2018; 53:iv-vi.

98. Kirkpatrick E, Qiu X, Wilson PC, Bahl J, Krammer F. The influenza virus hemagglutinin head evolves faster than the stalk domain. Scientific reports. 2018; 8(1):10432.

97. Zhang H, Henry C, Anderson CS, Nogales A, DeDiego ML, Bucukovski J, Martinez-Sobrido L, Wilson PC, Topham DJ, Miller BL. Crowd on a Chip: Label-Free Human Monoclonal Antibody Arrays for Serotyping Influenza. Analytical chemistry. 2018; 90(15):9583-9590.

96. Wilson PC, Cobey S. Characterization of the immunologic repertoire: A quick start guide. Immunological reviews. 2018; 284(1):5-8.

95. Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. Broadly Reactive Human Monoclonal Antibodies Elicited Following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Journal of virology. 2018; 92(16):e00949-18.

94. Guthmiller JJ, Wilson PC. Harnessing immune history to combat influenza viruses. Current opinion in immunology. 2018; 53:187-195.

93. Stamper CT, Wilson PC. What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Is Affinity Maturation a Self-Defeating Process for Eliciting Broad Protection? Cold Spring Harbor perspectives in biology. 2018; 10(5):a028803.

92. Chen YQ, Wohlbold TJ, Zheng NY, Huang M, Huang Y, Neu KE, Lee J, Wan H, Rojas KT, Kirkpatrick E, Henry C, Palm AE, Stamper CT, Lan LY, Topham DJ, Treanor J, Wrammert J, Ahmed R, Eichelberger MC, Georgiou G, Krammer F, Wilson PC. Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies. Cell. 2018; 173(2):417-429.e10.

91. Krammer F, Fouchier RAM, Eichelberger MC, Webby RJ, Shaw-Saliba K, Wan H, Wilson PC, Compans RW, Skountzou I, Monto AS. NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines? mBio. 2018; 9(2):e02332-17.

90. Henry C, Palm AE, Krammer F, Wilson PC. From Original Antigenic Sin to the Universal Influenza Virus Vaccine. Trends in immunology. 2018; 39(1):70-79.

89. Zost SJ, Parkhouse K, Gumina ME, Kim K, Diaz Perez S, Wilson PC, Treanor JJ, Sant AJ, Cobey S, Hensley SE. Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains. Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(47):12578-12583.

88. He W, Chen CJ, Mullarkey CE, Hamilton JR, Wong CK, Leon PE, Uccellini MB, Chromikova V, Henry C, Hoffman KW, Lim JK, Wilson PC, Miller MS, Krammer F, Palese P, Tan GS. Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice. Nature communications. 2017; 8(1):846.

87. Bunker JJ, Erickson SA, Flynn TM, Henry C, Koval JC, Meisel M, Jabri B, Antonopoulos DA, Wilson PC, Bendelac A. Natural polyreactive IgA antibodies coat the intestinal microbiota. Science. 2017; 358(6361).

86. DiPiazza A, Nogales A, Poulton N, Wilson PC, Martínez-Sobrido L, Sant AJ. Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo. Scientific reports. 2017; 7(1):10857.

85. Leon PE, Wohlbold TJ, He W, Bailey MJ, Henry CJ, Wilson PC, Krammer F, Tan GS. Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies. Journal of visualized experiments. 2017; (126): e56067.

83. Lau D, Lan LY, Andrews SF, Henry C, Rojas KT, Neu KE, Huang M, Huang Y, DeKosky B, Palm AE, Ippolito GC, Georgiou G, Wilson PC. Low CD21 expression defines a population of recent germinal center graduates primed for plasma cell differentiation. Science immunology. 2017; 2(7).

82. Canzar S, Neu KE, Tang Q, Wilson PC, Khan AA. BASIC: BCR assembly from single cells. Bioinformatics. 2017; 33(3):425-427.

81. Neu KE, Tang Q, Wilson PC, Khan AA. Single-Cell Genomics: Approaches and Utility in Immunology. Trends in immunology. 2017; 38(2):140-149.

80. Rivas JR, Ireland SJ, Chkheidze R, Rounds WH, Lim J, Johnson J, Ramirez DM, Ligocki AJ, Chen D, Guzman AA, Woodhall M, Wilson PC, Meffre E, White C 3rd, Greenberg BM, Waters P, Cowell LG, Stowe AM, Monson NL. Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients. Acta neuropathologica. 2017; 133(1):43-60.

79. Lee J, Boutz DR, Chromikova V, Joyce MG, Vollmers C, Leung K, Horton AP, DeKosky BJ, Lee CH, Lavinder JJ, Murrin EM, Chrysostomou C, Hoi KH, Tsybovsky Y, Thomas PV, Druz A, Zhang B, Zhang Y, Wang L, Kong WP, Park D, Popova LI, Dekker CL, Davis MM, Carter CE, Ross TM, Ellington AD, Wilson PC, Marcotte EM, Mascola JR, Ippolito GC, Krammer F, Quake SR, Kwong PD, Georgiou G. Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination. 2016; 22(12):1456-1464.

78. He W, Tan GS, Mullarkey CE, Lee AJ, Lam MM, Krammer F, Henry C, Wilson PC, Ashkar AA, Palese P, Miller MS. Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus. Proceedings of the National Academy of Sciences of the United States of America. 2016; 113(42):11931-11936.

77. Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, Sesterhenn F, Wilson PC, Galloway DM, Stanfield RL, Wilson IA, Burton DR, Schief WR. Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. PLoS pathogens. 2016; 12(8):e1005815.

76. Palm AK, Wilson PC. To B or not to B maintained? Blood. 2o16; 128(3):317-8.

75. Priyamvada L, Quicke KM, Hudson WH, Onlamoon N, Sewatanon J, Edupuganti S, Pattanapanyasat K, Chokephaibulkit K, Mulligan MJ, Wilson PC, Ahmed R, Suthar MS, Wrammert J. Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus. Proceedings of the National Academy of Sciences of the United States of America. 2016; 113(28):7852-7.

74. Ho IY, Bunker JJ, Erickson SA, Neu KE, Huang M, Cortese M, Pulendran B, Wilson
PC. Refined protocol for generating monoclonal antibodies from single human and
murine B cells. Journal of immunological methods. 2016; 438:67-70.

73. Neu KE, Henry Dunand CJ, Wilson PC. Heads, stalks and everything else: how can
antibodies eradicate influenza as a human disease? Current opinion in immunology.
2016; 42:48-55.

72. Priyamvada L, Cho A, Onlamoon N, Zheng NY, Huang M, Kovalenkov Y, Chokephaibulkit
K, Angkasekwinai N, Pattanapanyasat K, Ahmed R, Wilson PC, Wrammert J. B Cell
Responses during Secondary Dengue Virus Infection Are Dominated by Highly
Cross-Reactive, Memory-Derived Plasmablasts. Journal of virology. 2016;
90(12):5574-85.

71. Henry Dunand CJ, Leon PE, Huang M, Choi A, Chromikova V, Ho IY, Tan GS, Cruz J,
Hirsh A, Zheng NY, Mullarkey CE, Ennis FA, Terajima M, Treanor JJ, Topham DJ,
Subbarao K, Palese P, Krammer F, Wilson PC. Both Neutralizing and
Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies
Confer Protection. Cell host & microbe. 2016; 19(6):800-13.

70. Neu KE, Wilson PC. Taking the Broad View on B Cell Affinity Maturation. Immunity.
2016; 44(3):518-20.

69. DiLillo DJ, Palese P, Wilson PC, Ravetch JV. Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection. The Journal of clinical investigation. 2016; 126(2):605-10.

68. Andrews SF, Huang Y, Kaur K, Popova LI, Ho IY, et al. Immune history profoundly affects broadly protective B cell responses to influenza. Sci Transl Med. 2015 Dec 2;7(316):316ra192.

67. Victora GD, Wilson PC. Germinal Center Selection and the Antibody Response to Influenza. Cell. 2015; 163(3):545-8.

66. Bunker JJ, Flynn TM, Koval JC, Shaw DG, Meisel M, et al. Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A. Immunity. 2015; 43(3):541-53.

65. Henry Dunand CJ, Wilson PC. Restricted, canonical, stereotyped and convergent immunoglobulin responses. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2015; 370(1676).

64. Cobey S, Wilson P, Matsen FA 4th. The evolution within us. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2015; 370(1676).

63. Smith MJ, Packard TA, O’Neill SK, Henry Dunand CJ, Huang M, et al. Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients. Diabetes. 2015; 64(5):1703-12.

62. Henry Dunand CJ, Leon PE, Kaur K, Tan GS, Zheng NY, et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. The Journal of clinical investigation. 2015; 125(3):1255-68.

61. Andrews SF, Kaur K, Pauli NT, Huang M, Huang Y, et al. High preexisting serological antibody levels correlate with diversification of the influenza vaccine response. Journal of virology. 2015; 89(6):3308-17.

60. Kaur K, Zheng NY, Smith K, Huang M, Li L, et al. High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination. PloS one. 2015; 10(5):e0125618.

59. Kinloch AJ, Chang A, Ko K, Henry Dunand CJ, Henderson S, et al. Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis. Arthritis & rheumatology (Hoboken, N.J.). 2014; 66(12):3359-70. NIHMSID: NIHMS634048 PubMed [journal] PMID: 25306868, PMCID: PMC4264660

58. Pauli NT, Kim HK, Falugi F, Huang M, Dulac J, et al. Staphylococcus aureus infection induces protein A-mediated immune evasion in humans. The Journal of experimental medicine. 2014; 211(12):2331-9.

57. Linderman SL, Chambers BS, Zost SJ, Parkhouse K, Li Y, et al. Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season. Proceedings of the National Academy of Sciences of the United States of America. 2014; 111(44):15798-803.

56. Ellebedy AH, Krammer F, Li GM, Miller MS, Chiu C, et al. Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America. 2014; 111(36):13133-8.

55. Steinsbø Ø, Henry Dunand CJ, Huang M, Mesin L, Salgado-Ferrer M, et al. Restricted VH/VL usage and limited mutations in gluten-specific IgA of coeliac disease lesion plasma cells. Nature communications. 2014; 5:4041.

54. Magadán JG, Altman MO, Ince WL, Hickman HD, Stevens J, et al. Biogenesis of influenza a virus hemagglutinin cross-protective stem epitopes. PLoS pathogens. 2014; 10(6):e1004204.

53. Cowan M, Chon WJ, Desai A, Andrews S, Bai Y, et al. Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients. Transplantation. 2014; 97(8):846-53.

52. Krammer F, Albrecht RA, Tan GS, Margine I, Hai R, et al. Divergent H7 immunogens offer protection from H7N9 virus challenge. Journal of virology. 2014; 88(8):3976-85.

51. Bodewes R, Geelhoed-Mieras MM, Wrammert J, Ahmed R, Wilson PC, et al. In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein. Clinical and vaccine immunology : CVI. 2013; 20(8):1333-7.

50. Li Y, Myers JL, Bostick DL, Sullivan CB, Madara J, et al. Immune history shapes specificity of pandemic H1N1 influenza antibody responses. The Journal of experimental medicine. 2013; 210(8):1493-500.

49. Iversen R, Di Niro R, Stamnaes J, Lundin KE, Wilson PC, et al. Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells. Journal of immunology (Baltimore, Md. : 1950). 2013; 190(12):5981-91.

48. Smith K, Muther JJ, Duke AL, McKee E, Zheng NY, et al. Fully human monoclonal antibodies from antibody secreting cells after vaccination with Pneumovax®23 are serotype specific and facilitate opsonophagocytosis. Immunobiology. 2013; 218(5):745-54.

47. Chiu C, Wrammert J, Li GM, McCausland M, Wilson PC, et al. Cross-reactive humoral responses to influenza and their implications for a universal vaccine. Annals of the New York Academy of Sciences. 2013; 1283:13-21.

46. Brooke CB, Ince WL, Wrammert J, Ahmed R, Wilson PC, et al. Most influenza a virions fail to express at least one essential viral protein. Journal of virology. 2013; 87(6):3155-62.

45. Jiang N, He J, Weinstein JA, Penland L, Sasaki S, et al. Lineage structure of the human antibody repertoire in response to influenza vaccination. Science translational medicine. 2013; 5(171):171ra19.

44. DeKosky BJ, Ippolito GC, Deschner RP, Lavinder JJ, Wine Y, et al. High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire. Nature biotechnology. 2013; 31(2):166-9.

43. Andrews SF, Zhang Q, Lim S, Li L, Lee JH, et al. Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity. The Journal of experimental medicine. 2013; 210(1):125-42.

42. Perng GC. Role of Bone Marrow in Pathogenesis of Viral Infections. Journal of bone marrow research. 2012; 1.

41. Wilson PC, Andrews SF. Tools to therapeutically harness the human antibody response. Nature reviews. Immunology. 2012; 12(10):709-19.

40. Smith K, Crowe SR, Garman L, Guthridge CJ, Muther JJ, et al. Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization. Vaccine. 2012; 30(28):4276-83.

39. Li GM, Chiu C, Wrammert J, McCausland M, Andrews SF, et al. Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109(23):9047-52.

38. Issa RI, Griffin TM. Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation. Pathobiology of aging & age related diseases. 2012; 2(2012).

37. Li F, Chvyrkova I, Terzyan S, Wakeham N, Turner R, et al. Inhibition of anthrax lethal factor: lability of hydroxamate as a chelating group. Applied microbiology and biotechnology. 2012; 94(4):1041-9.

36. Wrammert J, Onlamoon N, Akondy RS, Perng GC, Polsrila K, et al. Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans. Journal of virology. 2012; 86(6):2911-8.

35. Di Niro R, Mesin L, Zheng NY, Stamnaes J, Morrissey M, et al. High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions. Nature medicine. 2012; 18(3):441-5.

34. Popova L, Smith K, West AH, Wilson PC, James JA, et al. Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses. PloS one. 2012; 7(7):e41895.

33. O’Donnell CD, Vogel L, Wright A, Das SR, Wrammert J, et al. Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice. mBio. 2012; 3(3).

32. Terajima M, Cruz J, Co MD, Lee JH, Kaur K, et al. Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies. Journal of virology. 2011; 85(24):13463-7.

31. Kaur K, Sullivan M, Wilson PC. Targeting B cell responses in universal influenza vaccine design. Trends in immunology. 2011; 32(11):524-31.

30. Sasaki S, Sullivan M, Narvaez CF, Holmes TH, Furman D, et al. Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies. The Journal of clinical investigation. 2011; 121(8):3109-19.

29. Wrammert J, Koutsonanos D, Li GM, Edupuganti S, Sui J, et al. Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. The Journal of experimental medicine. 2011; 208(1):181-93.

28. Pauli NT, Henry Dunand CJ, Wilson PC. Exploiting human memory B cell heterogeneity for improved vaccine efficacy. Frontiers in immunology. 2011; 2:77.

27. Sullivan M, Kaur K, Pauli N, Wilson PC. Harnessing the immune system’s arsenal: producing human monoclonal antibodies for therapeutics and investigating immune responses. F1000 biology reports. 2011; 3:17.

26. Di Niro R, Mesin L, Raki M, Zheng NY, Lund-Johansen F, et al. Rapid generation of rotavirus-specific human monoclonal antibodies from small-intestinal mucosa. Journal of immunology (Baltimore, Md. : 1950). 2010; 185(9):5377-83.

25. Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature. 2010; 467(7315):591-5.

24. Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, et al. The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell host & microbe. 2010; 8(3):271-83.

23. Andrews SF, Wilson PC. The anergic B cell. Blood. 2010; 115(24):4976-8.

22. Duty JA, Szodoray P, Zheng NY, Koelsch KA, Zhang Q, et al. Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. The Journal of experimental medicine. 2009; 206(1):139-51.

21. Smith K, Garman L, Wrammert J, Zheng NY, Capra JD, et al. Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen. Nature protocols. 2009; 4(3):372-84.

20. Wrammert J, Smith K, Miller J, Langley WA, Kokko K, et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature. 2008; 453(7195):667-71.

19. Jackson SM, Wilson PC, James JA, Capra JD. Human B cell subsets. Advances in immunology. 2008; 98:151-224.

18. Gaëta BA, Malming HR, Jackson KJ, Bain ME, Wilson P, et al. iHMMune-align: hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences. Bioinformatics (Oxford, England). 2007; 23(13):1580-7.

17. Teague BN, Pan Y, Mudd PA, Nakken B, Zhang Q, et al. Cutting edge: Transitional T3 B cells do not give rise to mature B cells, have undergone selection, and are reduced in murine lupus. Journal of immunology (Baltimore, Md. : 1950). 2007; 178(12):7511-5.

16. Koelsch K, Zheng NY, Zhang Q, Duty A, Helms C, et al. Mature B cells class switched to IgD are autoreactive in healthy individuals. The Journal of clinical investigation. 2007; 117(6):1558-65.

15. Crouch EE, Li Z, Takizawa M, Fichtner-Feigl S, Gourzi P, et al. Regulation of AID expression in the immune response. The Journal of experimental medicine. 2007; 204(5):1145-56.

14. Casellas R, Zhang Q, Zheng NY, Mathias MD, Smith K, et al. Igkappa allelic inclusion is a consequence of receptor editing. The Journal of experimental medicine. 2007; 204(1):153-60.

13. Kolar GR, Mehta D, Wilson PC, Capra JD. Diversity of the Ig repertoire is maintained with age in spite of reduced germinal centre cells in human tonsil lymphoid tissue. Scandinavian journal of immunology. 2006; 64(3):314-24.

12. Zheng NY, Wilson K, Jared M, Wilson PC. Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation. The Journal of experimental medicine. 2005; 201(9):1467-78.

11. Szodoray P, Jellestad S, Alex P, Zhou T, Wilson PC, et al. Programmed cell death of peripheral blood B cells determined by laser scanning cytometry in Sjögren’s syndrome with a special emphasis on BAFF. Journal of clinical immunology. 2004; 24(6):600-11.

10. Zheng NY, Wilson K, Wang X, Boston A, Kolar G, et al. Human immunoglobulin selection associated with class switch and possible tolerogenic origins for C delta class-switched B cells. The Journal of clinical investigation. 2004; 113(8):1188-201.

9. Meffre E, Schaefer A, Wardemann H, Wilson P, Davis E, et al. Surrogate light chain expressing human peripheral B cells produce self-reactive antibodies. The Journal of experimental medicine. 2004; 199(1):145-50.

8. Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, et al. AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching. Nature. 2001; 414(6864):660-5.

7. Rossi MI, Medina KL, Garrett K, Kolar G, Comp PC, et al. Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice. Journal of immunology (Baltimore, Md. : 1950). 2001; 167(6):3033-42.

6. Yannoutsos N, Wilson P, Yu W, Chen HT, Nussenzweig A, et al. The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo. The Journal of experimental medicine. 2001; 194(4):471-80.

5. Wilson PC, Wilson K, Liu YJ, Banchereau J, Pascual V, et al. Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes. The Journal of experimental medicine. 2000; 191(11):1881-94.

4. Wilson PC, Donald Capra J. The super-information age of immunoglobulin genetics. The Journal of experimental medicine. 1998; 188(11):1973-5.

3. Wilson P, Liu YJ, Banchereau J, Capra JD, Pascual V. Amino acid insertions and deletions contribute to diversify the human Ig repertoire. Immunological reviews. 1998; 162:143-51.

2. Wilson PC, de Bouteiller O, Liu YJ, Potter K, Banchereau J, et al. Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes. The Journal of experimental medicine. 1998; 187(1):59-70.

1. Pascual V, Wilson P, Liu YJ, Banchereau J, Capra JD. Biased VH4 gene segment repertoire in the human tonsil. Chemical immunology. 1997; 67:45-57.

PubMed

Last modified: October 21, 2019